HAIR LOSS IN MEN
About 85% of all men will experience some form of hair loss during their lifetime. There are many reasons for hair loss in men, but the main cause is male pattern balness.
Male Pattern Baldness (Androgenic Alopecia)
Male pattern balness occurs in about 95% of men who experience hair loss. It is a heriditary condition caused by genes from your parents. This gene affects how sensitive you are to a hormone called DHT. DHT makes your hair folliciles shrink, and as your hair folliciles shrink, the hair that grows back become smaller, thinner and shorter. Eventually no hair will grow out of the follicile. Male Pattern Baldness has a defining shape to the hair loss. First the receding hair line and eventually a horseshoe shape bald area on top of your scalp.
There are two over the counter drugs that have been approved for male pattern baldness, Minoxidil (Rogaine) and Finasteride (Propecia, Proscar).
This type of hair loss, often called spot baldness occurs because of an autoimmune disease. Unlike male pattern baldness which takes some time to lose your hair, you will notice spot baldness quicker. With spot baldness, your hair falls out in round patches. The good news it that it isn’t usually permanent and will grow back.
Cicatricial (Scarring) Alopecia
Scarring alopecia is a permanent hair loss that causes scarring of the hair follicles and destroys them. It accounts for approximately 3% of hair loss disorders. Scarring alopecia is caused by inflammation. The early stages of a scarring alopecia will have inflammatory cells around the hair follicles which induces the destruction of the hair follicles and development of scar tissue. It occurs worldwide in both healthy men and women of all ages.
The most common treatment for scarring alopecia is with antibiotics and isotretinoin.
Minoxidil is a topical solution you put on your scalp for hair loss. It comes in the brand name Rogaine® and can be effective in stopping hair loss if used as directed. Minoxidil is a vasodilator hypertension drug that is also used to help you regrow hair on your scalp. It’s mechanism of action is unknown but it is possible that it dilates blood vessels in the scalp, which may improve hair follicle function and stimulate hair growth. It doesn’t work for everyone. About 50 percent of patients who try it see hair growth, and that group is usually under 40 and in the beginning stages of hair loss. Minoxidil should be used twice a day, every day. Once you stop using it, the hair will stop growing and new growth will fall out. If you have an area that’s completely bald, minoxidil might not help restore lost hair in that area at all.
The 2 percent solution of minoxidil is approved by the FDA for use by women who are experiencing hair loss. The 5 percent solution isn’t FDA approved for women, for a few reasons. The 5 percent solution contains more ingredients that can trigger skin irritation or an allergic reaction. The stronger concentration also puts women at an increased risk for hypotension, or low blood pressure, which can cause dizziness and fainting. Minoxidil can also cause unwanted hair growth in women.
Because Minoxidil is a drug, there are side effects that should be known if you decide to use it:
- Scalp irritation, likely because of the product’s alcohol content
- Itchy scalp and dandruff
- Dizziness or rapid heartbeat (rare)
- Not recommended when the scalp is already irritated, injured or sunburned, which would allow the medication to be absorbed by the body at a higher and potentially dangerous level
- Formulated for scalp application and not recommended for use elsewhere on the body
- Effects on a fetus in women who are pregnant are unknown; however, women who are nursing are warned to not use it
- Minoxidil users with severe, refractory high blood pressure might experience hypertrichosis, which is hair growth on the face or other bodily areas. The incidence of this occurs in about 3-5 percent of women who use the 2 percent solution and higher among women using the 5 percent solution.
Finasteride is a pharmaceutical drug that prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. It comes in the brand name Propecia®. It is used to treat BPH and male pattern hair loss.
Finasteride should not be used by woman and can cause birth defects if handled by a woman during pregnancy. Caution should be used in older men who have benign prostatic hyperplasia (BPH), PSA levels are decreased by approximately 50%. Men aged 55 and over have increased risk of high grade prostate cancer with 5a-reductase inhibitors. Caution should be exercised in administration of Propecia in those patients with liver function abnormalities. Propecia is not indicated for use in pediatric patients.
Finasteride side effect include:
- loss of interest in sex
- trouble having an orgasm
- abnormal ejaculation
- swelling in your hands or feet
- swelling or tenderness in your breasts
- feeling like you might pass out
- runny nose
- skin rash
AAPE (Adipose-derived stem cells Proteins Extracts)
Another hair loss solution is AAPE. AAPE (Adipose-derived stem cells Proteins Extracts) is a safe hair regeneration treatment using adipose-derived conditioned medium. AAPE haircare serum is a non-invasive treatment that can be applied in a clinical setting without discomfort or downtime as a hair loss treatment. AAPE hair treatments can be used as a standalone treatment or combined with PRP (Platelet Rich Plasma). For more information about AAPE, click here
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